In reference to WKA Yung (Neuro-Oncology 2012; 14:1115)

Imaging in neuro-oncology

Imaging plays several key roles in managing brain tumors, including diagnosis, prognosis, and treatment response assessment. Ongoing challenges remain as new therapies emerge and there are urgent needs to find accurate and clinically feasible methods to noninvasively evaluate brain tumors before and after treatment. This review aims to provide an overview of several advanced imaging modalities ...

Hotspots in Neuro-Oncology

In reference to lamborn et Al. (Neuro-oncology. 2008;10:162-170).

Dear Editor, A recent article in this journal evaluating the significance of progression-free survival as a major end point in neuro-oncology clinical trials (Progression-free survival: An important end point in evaluating therapy for recurrent high-grade gliomas [Neuro-Oncology 2008;10: 162–170]) stated that, due to the lack of validated instruments for the assessment of symptomatic end points...

Monoclonal antibodies in neuro-oncology

Monoclonal antibodies (mAbs) are used with increasing success against many tumors but, for brain tumors, the blood-brain barrier (BBB) is a special concern. The BBB prevents antibody entry to the normal brain; however, its role in brain tumor therapy is more complex. The BBB is closest to normal at micro-tumor sites; its properties and importance change as the tumor grows. In this review, evolv...

Neuro-oncology: an overview.

The direct, indirect, and treatment-related effects of cancer on the nervous system have received variable attention by neurologists over the past century. The diseases encompassed in the neuro-oncology field and our understanding of them have increased rapidly during the past 30 years. In part, progress has been driven by technological achievements in neuroimaging, in particular, computed tomo...